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White Paper
White Paper: Gene Therapy Research and Humanized Mouse Models
Sep 26, 2021
In Cyagen's exclusive White Paper, our experts briefly introduce the background of gene therapy for rare diseases and explore the applications of humanized mouse models for genetic diseases. Read More >
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Newsletter
White Paper
Applications of the Mouse Model in Translational Medical Research
Nov 16, 2020
The mouse model has become an irreplaceable model organism for biomedical research, which includes studying gene function and genetic factors of pathogenesis, establishing humanized disease models, and evaluating the safety and effectiveness of drugs under development. Read More >
White Paper
Research Trend
Conditional Rat Models for Human Disease Research
Sep 21, 2020
Rats are an ideal animal model for human disease research – compared to mice, rats are physiologically, morphologically, and genetically closer to humans – as covered in our recent Technical Bulletin. Since the first targeted knockout (KO) rat was developed in 2010, significant progress has been made in their use as experimental model animals in basic research, drug screenings, and preclinical drug evaluations. Read More >
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Research Trend
Animal Models of Non-Alcoholic Fatty Liver Disease (NAFLD) and Steatohepatitis (NASH)
Jun 04, 2020
Non-alcoholic fatty liver disease (NAFLD), a hepatopathy syndrome affecting both adults and children, is characterized by a range of liver conditions affecting people who consume little to no alcohol, including simple fatty liver, steatohepatitis, fatty liver fibrosis, and cirrhosis. NAFLD can progress from simple fatty liver through nonalcoholic steatohepatitis (NASH) to liver fibrosis, and even lead to end-stage liver diseases, such as, liver cirrhosis, hepatocellular carcinoma (HCC), or liver failure. Read More >
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Latest Discovery
COVID-19
Understanding SARS-CoV-2: From the Origin to Current Research
May 13, 2020
The coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become an ongoing global health emergency. Herein, we track the virus from its origin to current research efforts, with the aim of providing inspiration for further research and vaccine development. Read More >
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White Paper
COVID-19
Complete Collection: The Hottest Mouse Models for Coronavirus Research
Apr 10, 2020
The World Health Organization (WHO) announced the reclassification of the COVID-19 outbreak as a global pandemic on March 11, 2020. With the rapid spread of the disease across the globe, countries worldwide have joined the war against the SARS-CoV-2 virus, for which, early prevention, control, and treatment may provide valuable tools against the pandemic. Read More >
Newsletter
Research Trend
White Paper
COVID-19
Researching the New Coronavirus, SARS-CoV-2: Applications for Animal Models
Mar 10, 2020
The novel coronavirus, now officially designated as SARS-CoV-2, was first identified in Wuhan, Hubei Province, China in December of 2019. This virus has led to an outbreak of COVID-19 (Coronavirus Disease in 2019), which is associated with acute respiratory illness and infection, as is common for diseases caused by the coronavirus family. Read More >
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Breaking News
White Paper
COVID-19
Coronaviruses and SARS-CoV-2 – Host Receptor-Mediated Infection Mechanisms & Potential Antiviral Treatments
Mar 10, 2020
At the end of 2019, a large-scale illness broke out from Wuhan, Hubei Province - a central province of China. The virus that cased this illness could enter the respiratory tract through droplets - moreover, the increasingly busy traffic conditions and travel around the holiday season made the virus spread extremely rapidly. Read More >
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Breaking News
White Paper
COVID-19
Beyond ACE2: Additional Targets of Significance for Coronavirus Research
Mar 10, 2020
At present, the prevention and treatment of coronavirus is the most urgent issue for scientific and medical research. In addition to the ACE2 host receptor target that is being highly focused on, what other targets deserve the attention of current coronavirus researchers? Read More >
Research Trend
Breaking News
White Paper
COVID-19
White Paper: Infectivity and Immune Mechanisms of Coronaviruses & SARS-CoV-2
Feb 27, 2020
An outbreak of COVID-19 (Coronavirus Disease in 2019) caused by the novel coronavirus, officially named SARS-CoV-2, swept across the world from Wuhan at the end of 2019 - having since brought a huge impact on the lives of people both in China and abroad. Read More >